GIDeCA

Head and Coordination

Team

Funding

Loewe Logo

Duration

09/2011 - 09/2014

Project GIDeCA

Gene by Environment Interactions on Decision Making in Children with Different ADHD Symptoms

GIDeCA assessed biological and psychosocial family-related influences on the ability to delay rewards and on risky decision-making behavior in children with different ADHD symptoms.

Children with Attention Deficit Hyperactivity Disorder (ADHD) are known to be exceedingly impulsive. For instance, they prefer receiving a small gift immediately instead of waiting for a bigger gift they will receive later on. In addition, they decide in favor of options that offer a large gain but are unlikely to be reached, rather than voting for options with a high probability for a small gain.

Different gene variants correlate with a reduced ability to delay rewards and with risky decision making. Moreover, there is evidence that psychosocial and family-related aspects have an influence on the ability to delay a reward.

We assumed that genetic as well as psychosocial and family-related factors correlate with the ability to delay rewards and risky decision-making. Furthermore, we assumed that the effects of family-related risk factors are particularly significant in individuals with a particular genetic disposition.

115 children aged between eight and twelve years participated in the study. They were assessed thoroughly by psychologists. Furthermore, saliva samples were obtained from the children for a molecular-genetic test and the parents and children worked on a task together. The ability to delay rewards and risky decision-making behavior was assessed by means of playful and partly computer-based tasks the children generally enjoy.

Selected Publication and Poster

Reinelt, T. (2015). Beyond Endophenotypes: Direct and Indirect Effects of Sustained Attention and Behavioral Inhibition on Attention Deficit Hyperactivity Disorder (Dissertation). Eberhard Karls University of Tübingen, Faculty of Science.

Reinelt, T., Wirth, A., Rauch, W., & Gawrilow, C. (2014, April). Duration Discrimination predicts delay of gratification in children with and without ADHD. Poster presented at the conference on Timing and Time Perception. Corfu, Greece. (Poster)